Welcome to the TCNLab. The driving force behind all of the work in our lab is exactly as the name suggests: we want to understand the neuroscience of cognition, and to facilitate translation of that understanding from animal models to humans and back again. Historically our interest has been in the basic research question: What is the organization, and what are the mechanisms, underlying cognition in the brain? We like to think we have come up with some answers, but to do so, we have needed to develop some new methodologies … some of which you can find out about in more detail here.

More recently we have expanded our activities to include more applied research, transferring the knowledge, and especially the methodologies, gained from our basic research stream, into the areas of neuropsychiatric and neurodegenerative disease and drug discovery.

We are a highly collaborative laboratory, and enjoy productive working relationships with a number of researcher groups and consortia – more details of which you can read about here.

The TCNLab is part of the Department of Psychology and the Behavioural and Clinical Neuroscience Institute at the University of Cambridge. We are currently funded by the BBSRC, the MRC, the Wellcome Trust, the European Commission and Janssen Pharma.

Recent News

In touch with the Mind

"Because we study behaviour, the lab has to be quite big,” Lisa Saksida, PhD, explained as she and her partner Tim Bussey, PhD, walk through their brand new work environment at Schulich Medicine & Dentistry’s Robarts Research Institute.

It's All in Our Heads

Saksida wants to understand how brain circuits are altered in Alzheimer’s Disease. Drug treatment for Alzheimer’s only treats symptoms. There is still no proven therapy that stops or reverses progression of Alzheimer’s. Saksida believes the key to effective treatments is to better understand the brain circuits involved so that they can be targeted to improve cognition.